Friday, August 23, 2019

Obsessive Compulsive Disorder Annotated Bibliography

Obsessive Compulsive Disorder - Annotated Bibliography Example in-reuptake inhibitors on (OCD) are adequate to deduce that a serotonin regulatory disorder is the most vital piece of the pathophysiology of OCD (2011). However, patients with OCD will require a high dosage of serotonin-reuptake inhibitor monotherapy. This may sometimes not be ample, and about half of patients are resistant to the treatment. The author states that previous studies indicate positive treatment reaction to dopaminergic antagonists. He infers that other neurotransmitter structures, like dopamine, are implicated in the pathophysiology of OCD. Evidence from Preclinical, neuroimaging and neurochemical researches demonstrates that the dopaminergic system is concerned in stirring up or infuriating indications pinpointing presence of OCD. The article reviews the dopaminergic system in OCD pathophysiology while reviewing the outcome of drugs that act on dopaminergic activity in OCD. Barrett PM, Farrell L, Pina AA, Peris TS, Piacentini J. (2008).Evidence-based psychosocial treatments for child and adolescent obsessive-compulsive disorder. Journal of Clinical Child and Adolescent Psychology. 237:131–155. In this article, the authors state that the development of fear habituation and disappearance are thought to be related to the pathophysiology of anxiety disorders. This includes obsessive-compulsive disorder (OCD), panic disorder, and posttraumatic stress disorder. The articles reports adjustments of auditory P50 suppression in human beings fear conditioning and extinction in fit control subjects. Furthermore, they report that P50 suppression in fear extinction is impaired in patients with OCD. The report explores investigations on the association between sensory gating and fear conditioning. Sensory gating mechanisms may be physiologically associated with fear conditioning, and OCD may involve abnormal sensory gating in fear extinction (Barret et al, 2008). Bloch, M. H., Williams, K and Pittenger, C. (2011). Glutamate abnormalities in obsessive

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